Medication Supported Language Therapy

The goal of this study is to examine whether a selective-serotonin reuptake inhibitor (SSRI) medication, called escitalopram, may help language therapy be even more effective when patients are recovering from stroke.

Please Note
This information is provided to help you make a decision about participating in research in general.
The decision to join a study is between you and the individual study research team.
Study research team members will provide detailed information and answer any questions you have.

Who can participate?

This study is designed for adults who...

  • Had a recent stroke on the left side of their brain
    Have aphasia, or difficulty speaking after stroke
    Speak English fluently
    Are right-handed
  • It may not be safe to participate if you...

    Have certain other diagnoses that impact your heart, brain, or mental health
    Have significant difficulty seeing or hearing
    Take certain medications
    Are pregnant or planning to become pregnant soon

When do I start?

Participation starts within the first 7 days after stroke

How long will I be followed?

  • Critical Care
  • Stroke Center
  • Discharge

Key activities

You will be asked to...

Participate in communication assessments
Take the study medication for 90 days as directed (free of charge)
Participate in language treatment as directed (free of charge)
Return to the outpatient center for two health monitoring visits after discharge
You may have the option to have a picture taken of your brain (MRI) or provide a genetic sample

Important information

You should know...

Participation is your choice and you can stop any time
Participation will not change your routine health care
If you experience certain changes to your health or must take other medications, you may be told you can no longer participate.

Details of the study will be provided by the study team members

Where can I learn more?

  • If you are interested in research, please tell your provider or contact us.

  • Study contacts

    Argye Hillis-Trupe, M.D.
    Melissa D. Stockbridge, Ph.D.
  • This study is funded by and registered with the U.S. National Institutes of Health.
    Click here to learn more.